POLYCLONAL NAPSIN A

Code: 352A-74 D2-231

General description

Napsin is a pepsin-like aspartic proteinase, in the A1 clan of the AA clade of proteinases. There are two closely related napsins, napsin A and napsin B. ...


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General description

Napsin is a pepsin-like aspartic proteinase, in the A1 clan of the AA clade of proteinases. There are two closely related napsins, napsin A and napsin B. Napsin A is expressed as a single chain protein with the molecular weight of approximately 38 kDa. Immunohistochemical studies revealed high expression levels of napsin A in human lung and kidney but low expression in spleen. Napsin A is expressed in type II pneumocytes and in adenocarcinomas of lung. The high specificity expression of napsin A in adenocarcinomas of lung is useful to distinguish primary lung adenocarcinomas from adenocarcinomas of other organs.

Legal Information

Cell Marque is a trademark of Sigma-Aldrich Co. LLC

Linkage

Napsin A Positive Control Slides, Product No. 352S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Other Notes

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Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and ﹤0.1% Sodium Azide

Preparation Note

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Quality

IVDIVDIVDRUO

antibody formIg fraction of antiserum
antibody product typeprimary antibodies
biological sourcerabbit
clonepolyclonal
conjugateunconjugated
controlkidney, lung adenocarcinoma
descriptionFor In Vitro Diagnostic Use in Select Regions (See Chart)
formbuffered aqueous solution
manufacturer/tradenameCell Marque
packagingvial of 0.5 mL concentrate (352A-75), vial of 1.0 mL concentrate (352A-76), vial of 0.1 mL concentrate (352A-74), bottle of 7.0 mL predilute (352A-78), bottle of 1.0 mL predilute (352A-77)
Quality Level100, 500
shipped inwet ice
species reactivityhuman
storage temp.2-8°C
technique(s)immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500
visualizationcytoplasmic
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